Coptis Roots 10% Berberine Extract Powder 1Kg

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Rabbani G. Mechanism and treatment of diarrhoea due to Vibrio cholerae and Escherichia coli: roles of drugs and prostaglandins. Danish Medical Bulletin 1996;43:173-185.

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People with Type 2 diabetes often have high blood glucose levels ( hyperglycemia), which can happen if: Berberine plays a role in decreasing total cholesterol, LDL cholesterol, and blood triglycerides while increasing HDL cholesterol. 24 25 It also lowers high blood pressure, supporting good heart health from every angle. The positive impacts berberine has on obesity and blood sugar could also work hand-in-hand to help prevent heart disease. And interestingly, berberine appears to have an anti-apoptotic effect on heart cells, which can keep the cells from dying prematurely. Xin, H. W., Wu, X. C., Li, Q., Yu, A. R., Zhong, M. Y., and Liu, Y. Y. The effects of berberine on the pharmacokinetics of cyclosporin A in healthy volunteers. Methods Find.Exp.Clin Pharmacol 2006;28(1):25-29. View abstract.Berberine works at a cellular level and changes how cells work by turning things off and on,” Dr. Bradley explains. “Its basic interactions involve so many different processes in the body.”

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Hui, K. K., Yu, J. L., Chan, W. F., and Tse, E. Interaction of berberine with human platelet alpha 2 adrenoceptors. Life Sci. 1991;49(4):315-324. View abstract. It requires a strict dosage regimen. Berberine has a short half-life of several hours — half the dose will be metabolized and eliminated from your system within a few hours. To keep blood levels stable and benefit from berberine, spread the daily dosage (up to 1.5 grams or 1,500 milligrams daily) throughout the day. Dr. Bradley recommends taking it three times a day before meals. Wang, D. Y., Yeh, C. C., Lee, J. H., Hung, C. F., and Chung, J. G. Berberine inhibited arylamine N-acetyltransferase activity and gene expression and DNA adduct formation in human malignant astrocytoma (G9T/VGH) and brain glioblastoma multiforms (GBM 8401) cells. Neurochem.Res 2002;27(9):883-889. View abstract. Krol R, Zalewski A, and Maroko PR. Beneficial effects of berberine, a new positive inotropic agent, on digitalis-induced ventricular arrhythmias. Circulation 1982;66(suppl 2):56. Lahiri S and Dutta NK. Berberine and chloramphenicol in the treatment of cholera and severe diarrhoea. Journal of the Indian Medical Association 1967;48(1):1-11.Khin, Maung U., Myo, Khin, Nyunt, Nyunt Wai, Aye, Kyaw, and Tin, U. Clinical trial of berberine in acute watery diarrhoea. Br.Med.J.(Clin.Res.Ed) 12-7-1985;291(6509):1601-1605. View abstract.

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Lin, J. G., Chung, J. G., Wu, L. T., Chen, G. W., Chang, H. L., and Wang, T. F. Effects of berberine on arylamine N-acetyltransferase activity in human colon tumor cells. Am J Chin Med 1999;27(2):265-275. View abstract. Wu, J. F. and Liu, T. P. [Effects of berberine on platelet aggregation and plasma levels of TXB2 and 6-keto-PGF1 alpha in rats with reversible middle cerebral artery occlusion]. Yao Xue.Xue.Bao. 1995;30(2):98-102. View abstract. Hu, F. L. [Comparison of acid and Helicobacter pylori in ulcerogenesis of duodenal ulcer disease]. Zhonghua Yi.Xue.Za Zhi. 1993;73(4):217-9, 253. View abstract. Chen C, Tao C, Liu Z, Lu M, Pan Q, Zheng L, et al. A randomized clinical trial of berberine hydrochloride in patients with diarrhea-predominant irritable bowel syndrome. Phytother Res. 2015 Nov;29(11):1822-7. doi: 10.1002/ptr.5475. View abstract. Xu, L., Liu, Y., & He, X. (2005). Inhibitory effects of berberine on the activation and cell cycle progression of human peripheral lymphocytes. Cellular & molecular immunology, 2(4), 295–300.Wang, N., Feng, Y., Cheung, F., Chow, O. Y., Wang, X., Su, W., and Tong, Y. A comparative study on the hepatoprotective action of bear bile and Coptidis Rhizoma aqueous extract on experimental liver fibrosis in rats. BMC.Complement Altern.Med 2012;12:239. View abstract. If you’re in the military, a teacher, or a first responder, PureBulk offers a 15% discount. You’ll need to verify your identity through VerifyPass, a third-party platform, and upon approval, you’ll get a one-time discount code valid for 24 hours. You’ll need to repeat this process to get another code each time you shop with PureBulk. Yin, J., Xing, H., & Ye, J. (2008). Efficacy of Berberine in Patients with Type 2 Diabetes. Metabolism: Clinical and Experimental, 57(5), 712. Subbaiah TV and Amin AH. Effect of berberine sulphate on Entamoeba histolytica. Nature 1967;215(100):527-528. Nishida, S., Kikuichi, S., Yoshioka, S., Tsubaki, M., Fujii, Y., Matsuda, H., Kubo, M., and Irimajiri, K. Induction of apoptosis in HL-60 cells treated with medicinal herbs. Am J Chin Med 2003;31(4):551-562. View abstract.

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Hong, Y., Hui, S. S., Chan, B. T., and Hou, J. Effect of berberine on catecholamine levels in rats with experimental cardiac hypertrophy. Life Sci. 4-18-2003;72(22):2499-2507. View abstract. Abe, F., Nagafuji, S., Yamauchi, T., Okabe, H., Maki, J., Higo, H., Akahane, H., Aguilar, A., Jimenez-Estrada, M., and Reyes-Chilpa, R. Trypanocidal constituents in plants 1. Evaluation of some Mexican plants for their trypanocidal activity and active constituents in Guaco, roots of Aristolochia taliscana. Biol Pharm Bull 2002;25(9):1188-1191. View abstract. Purohit SK, Kochar DK, Lal BB, and et al. Cultivation of Leishmania tropica from untreated and treated cases of oriental sore. Indian Journal of Public Health 1982;26(1):34-37. Trimarco, V., Cimmino, C. S., Santoro, M., Pagnano, G., Manzi, M. V., Piglia, A., Giudice, C. A., De, Luca N., and Izzo, R. Nutraceuticals for blood pressure control in patients with high-normal or grade 1 hypertension. High Blood Press Cardiovasc.Prev. 9-1-2012;19(3):117-122. View abstract. An Y, Sun Z, Zhang Y, Liu B, Guan Y, Lu M. The use of berberine for women with polycystic ovary syndrome undergoing IVF treatment. Clin Endocrinol (Oxf) 2014;80(3):425-31. View abstract.

Another significant benefit of berberine is its protection against heart disease. 22 While we don’t know for sure if it can stop heart failure, we do know that it can decrease the likelihood of: Kulkarni, S. K., Dandiya, P. C., and Varandani, N. L. Pharmacological investigations of berberine sulphate. Jpn.J Pharmacol. 1972;22(1):11-16. View abstract. Wu, S. N., Yu, H. S., Jan, C. R., Li, H. F., and Yu, C. L. Inhibitory effects of berberine on voltage- and calcium-activated potassium currents in human myeloma cells. Life Sci 1998;62(25):2283-2294. View abstract. Yang, J., Yin, J., Gao, H., Xu, L., Wang, Y., Xu, L., & Li, M. (2011). Berberine Improves Insulin Sensitivity by Inhibiting Fat Store and Adjusting Adipokines Profile in Human Preadipocytes and Metabolic Syndrome Patients. Evidence-based Complementary and Alternative Medicine: ECAM, 2012. A digestive tract infection that can lead to ulcers ( Helicobacter pylori or H. pylori). Adding berberine by mouth to multiple medications that are typically used to treat this condition might work as well as other accepted treatments for this condition. These other treatments also use multiple medications.